Fine Biotech is an ISO9001:2008 Certified Company,offers a full line of quality research kits,which include ELISA Kits,related ELISA assistant reagents and more high quality antibodies, recombinant proteins. Fine Biotech technical support are delicated to providing with professional and friendly assistance for our customers. Strict and multiple quality control ensure that our products continue to successfully supply for the international market. Moreover, we strive to continuously improve the customer experience through comprehensive technical support. High quality,rapid turnaround and personal support for all FineTest services are guaranteed. Should you have any problems,or any ideas on ways that we can improve our service,please feel free to call upon us.Thank you for your interest in FineTest products and we look forward to supplying you in the near future.Anti-TGFBR2 antibody(DMC467), IgG1 Chimeric mAb DMC100467
Specifications
| 10µg / 100µg / 500µg |
Background:
The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq, Aug 2017]
Synonyms:
AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TBR-ii, TBRII, TGFbeta-RII, TGFR-2
Clonality:
Monoclonal
Species reactivity:
Human
Host species:
Rabbit
Taraget:
TGFBR2
Isotype:
Rabbit/Human Fc chimeric IgG1
Purification:
Purified from cell culture supernatant by affinity chromatography
Applications:
Flow Cyt
Recommended dilution:
Flow Cyt 1/100
Formulation:
Liquid
Precaution:
Research use only
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com