Fine Biotech is an ISO9001:2008 Certified Company,offers a full line of quality research kits,which include ELISA Kits,related ELISA assistant reagents and more high quality antibodies, recombinant proteins. Fine Biotech technical support are delicated to providing with professional and friendly assistance for our customers. Strict and multiple quality control ensure that our products continue to successfully supply for the international market. Moreover, we strive to continuously improve the customer experience through comprehensive technical support. High quality,rapid turnaround and personal support for all FineTest services are guaranteed. Should you have any problems,or any ideas on ways that we can improve our service,please feel free to call upon us.Thank you for your interest in FineTest products and we look forward to supplying you in the near future.Anti-FCGR3A antibody(DMC219), IgG1 Chimeric mAb DMC100219
Specifications
| 10µg / 100µg / 500µg |
Background:
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms:
FCGR3A,CD16A,FCG3,FCGR3,IGFR3
Clonality:
Monoclonal
Species reactivity:
Human
Host species:
Rabbit
Taraget:
FCGR3A
Isotype:
Rabbit/Human Fc chimeric IgG1
Purification:
Purified from cell culture supernatant by affinity chromatography
Applications:
ELISA|Flow Cyt
Recommended dilution:
ELISA 1/5000-10000;Flow Cyt 1/100
Formulation:
Liquid
Precaution:
Research use only
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com