Fine Biotech is an ISO9001:2008 Certified Company,offers a full line of quality research kits,which include ELISA Kits,related ELISA assistant reagents and more high quality antibodies, recombinant proteins. Fine Biotech technical support are delicated to providing with professional and friendly assistance for our customers. Strict and multiple quality control ensure that our products continue to successfully supply for the international market. Moreover, we strive to continuously improve the customer experience through comprehensive technical support. High quality,rapid turnaround and personal support for all FineTest services are guaranteed. Should you have any problems,or any ideas on ways that we can improve our service,please feel free to call upon us.Thank you for your interest in FineTest products and we look forward to supplying you in the near future.Anti-BCL2L1 antibody(DM189), Rabbit mAb DME100189
Specifications
| 10µg / 100µg / 500µg |
Background:
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
Synonyms:
Bcl-X, BCL-XL/S, BCL2L, BCLX, PPP1R52
Clonality:
Monoclonal
Species reactivity:
Human
Host species:
Rabbit
Taraget:
BCL2L1
Isotype:
Rabbit IgG
Purification:
Purified from cell culture supernatant by affinity chromatography
Applications:
ELISA|Flow Cyt
Recommended dilution:
ELISA 1/5000-10000;Flow Cyt 1/100
Formulation:
Liquid
Precaution:
Research use only
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com