Background:

ACTR10 (Actin-related protein 10), also known as ARP11 or HARP11, is a 417 amino acid protein that localizes to the cytoplasm and the cytoskeleton and belongs to the Actin family. The gene that encodes ACTR10 maps to human chromosome 14, which contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, a disorder characterized by severe lung complications and liver dysfunction.

Specificity:

ACTR10 polyclonal antibody detects endogenous levels of ACTR10 protein.

Alternative names:

ACTR11;Arp10;Arp11;HARP11

Species reactivity:

Human,Mouse,Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of human ACTR10

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

46kDa

Applications:

WB

Usage:

WB 1:500 - 1:2000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

More info:

Email: info@sobekbio.com

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