Background:

KIAA0391, also known as MRPP3 (mitochondrial ribonuclease P protein 3), is a 583 amino acid protein that is located in the mitochondria. KIAA0391 functions in tRNA maturation and is a component of mitochondrial ribonuclease P which cleaves tRNA at the 5'-end. Mitochondrial ribonuclease P is an enzyme composed of RG9MTD1, MRPP22 and KIAA0391 subunits. Due to alternative splicing events, KIAA0391 exists as four isoforms. The gene encoding KIAA0391 maps to human chromosome 14, which contains about 700 genes and makes up about 3.5% of human cellular DNA.

Specificity:

KIAA0391 polyclonal antibody detects endogenous levels of KIAA0391 protein.

Alternative names:

MRPP3; PRORP; Mitochondrial ribonuclease P protein 3

Species reactivity:

Rat

Host:

Rabbit

Ig type:

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Immunogen:

Recombinant protein of human KIAA0391.

Purification & Purity:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Molecular weight:

~ 67 kDa

Applications:

WB

Usage:

WB 1:500 - 1:2000

Storage:

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Precautions:

For research use only, not for use in diagnostic procedure.

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