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Specifications
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CAS Number:
1095382-05-0
Target:
Aurora Kinase
Molecular formula:
C26H31BrN8O
Formula weight:
551,4813
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
A potent, orally bioavailable Aurora kinases inhibitor with IC50 of 15/25/19 nM for Aurora A/B/C; displays antiproliferative activity in a range of human tumor cell lines, including SW620 colon carcinoma (GI50=0.30 uM) and A2780 ovarian cancer cell line (GI50=0.14 uM); exhibits in vivo efficacy with no observed toxicities in SW620 colon carcinoma xenografts.
Note:
Research use only, not for human use.
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