Background:

IL18, is a proinflammatory cytokine involved in the development of Th1 cells and in immune response. It can stimulate the NK cells and certain T cells to release interferon gamma which plays an important role in activating the macrophages or other cells. IL18 has been demonstrated to have the potential to enhance Fas ligand-mediated cytotoxicity, which is increased in PE and regulates placental apoptosis. IL18 is synthesized as a 24 kDa precursor and then cleaved into a biologically activate 18 kDa form. This antibody is raised against the full length IL18 precursor, and it recognizes both the pre-IL18 and mature IL18 theoretically.

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

Iboctadekin, IFN gamma inducing factor, IGIF, IL 1 gamma, IL 18, IL 1g, IL18, IL1F4, Interleukin 1 gamma, Interleukin 18, Mature IL18, pre IL18

Specificity:

Human, Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

interleukin 18(interferon-gamma-inducing factor)

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

24 kDa

Form:

liquid

Applications:

ELISA, WB, IP, IHC, IF

Recommended dilution:

WB: 1:500-1:2000; IP: 1:500-1:5000 ; IHC: 1:50-1:500; IF: 1:10-1:100

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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