Background:

MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators. The antibody recognizes the C-term of MUC16.

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

CA 125, CA125, FLJ14303, MUC 16, MUC16, Mucin 16

Specificity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

mucin 16, cell surface associated

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

90-100 kDa

Form:

liquid

Applications:

ELISA, WB, IP,IHC

Recommended dilution:

WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:50-1:500

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

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