anti- DHRS2 antibody FNab02371
Background:
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
Clonality:
polyclonal
Classification:
Primary antibody
Alternative names:
SDR25C1
Specificity:
Human
Host:
Rabbit
Isotype:
IgG
Immunogen:
dehydrogenase/reductase(SDR family) member 2
Purification:
Immunogen affinity purified
Purity:
≥95% as determined by SDS-PAGE
Calculated molecular weight:
30 kDa
Form:
liquid
Applications:
ELISA, WB
Recommended dilution:
Request info at info@sobekbio.com
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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