Background:

Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly(PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase(MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation(PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma(HCC) cells(PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis(PubMed:25964343).

Clonality:

polyclonal

Classification:

Primary antibody

Alternative names:

CN2, CPGL, HEL-S-13, PEPA

Specificity:

Human, Mouse, Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

CNDP dipeptidase 2(metallopeptidase M20 family)

Purification:

Immunogen affinity purified

Purity:

≥95% as determined by SDS-PAGE

Calculated molecular weight:

54 kDa

Form:

liquid

Applications:

ELISA, WB, IF

Recommended dilution:

Request info at info@sobekbio.com

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

More info:

Email: info@sobekbio.com

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