anti- BMI1 antibody FNab00913
Background:
Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Clonality:
polyclonal
Classification:
Primary antibody
Alternative names:
PCGF4, RNF51
Specificity:
Human, Mouse
Host:
Rabbit
Isotype:
IgG
Immunogen:
BMI1 polycomb ring finger oncogene
Purification:
Immunogen affinity purified
Purity:
≥95% as determined by SDS-PAGE
Calculated molecular weight:
43-45 kDa
Form:
liquid
Applications:
ELISA, WB, IHC, IF, IP
Recommended dilution:
Request info at info@sobekbio.com
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
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