Background:

Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies.

Alternative names:

Bsh, CG17927, Dm II, Dmel\CG17927, DmMHC, DROMHC, DroMII, FBgn0002741, Ifm(2)2, l(2)36Ae, l(2)k10423, l(2)M66, Mhc, Mhc36B, mMHC, MRP, Myo, Myosin heavy chain, Nup, Sht, sMHC, Stp

Clonality:

Monoclonal

Species reactivity:

Human, Mouse, Rat, Fruit Fly, Nematode

Source:

Mouse

Species:

Human

Cellular localization:

Cytoplasm, Thick filament

Isotype:

IgG1

Immunogen:

Synthetic Peptide

Concentration:

1mg/ml

Observed band:

220kDa

Applications:

IHC, IF

Recommended dilution:

IHC 1:200 IF 1:100

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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