Background:

Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.

Alternative names:

Abeta degrading protease, insulin degrading enzyme, Insulin protease, Insulinase, INSULYSIN

Clonality:

Monoclonal

Species reactivity:

Human

Source:

Mouse

Species:

Human

Cellular localization:

Cell membrane, Cytoplasm, Membrane, Secreted

Isotype:

IgG1

Immunogen:

Synthetic Peptide

Concentration:

1mg/ml

Observed band:

118kDa

Applications:

WB, IHC

Recommended dilution:

WB 1:1,000 IHC 1:200

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

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