Background:

Galectin 3 is one of the more extensively studied members of this family and is a 30 kDa protein. Due to a C-terminal carbohydrate binding site, Galectin 3 is capable of binding IgE and mammalian cell surfaces only when homodimerized or homooligomerized. Galectin 3 is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins.

Alternative names:

35 kDa lectin, CBP 35, CBP35, Gal 3, GAL3, Galactose specific lectin 3, Galactoside binding protein, GALBP, Galectin 3, Galectin-3, GALIG, IgE binding protein, L 31, Laminin binding protein, Lectin L 29, LGALS2, LGALS3, Mac 2 antigen, MAC2

Clonality:

Monoclonal

Species reactivity:

Human, Mouse

Source:

Mouse

Species:

Human

Cellular localization:

Cytoplasm, Nucleus, Secreted, Spliceosome

Isotype:

IgG1

Immunogen:

Protein

Concentration:

1mg/ml

Observed band:

26kDa

Applications:

WB, IHC, ELISA

Recommended dilution:

WB  1:1,000-2,000      IHC 1:100-200     ELISA  10,000-50,000

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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