Background:

Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.

Alternative names:

AD8, Cystatin3, Gamma trace, HCCAA

Clonality:

Monoclonal

Species reactivity:

Human

Source:

Mouse

Species:

Human

Cellular localization:

Secreted

Isotype:

IgG1

Immunogen:

Recombinant Protein

Concentration:

1mg/ml

Observed band:

14kDa

Applications:

WB, IHC, ELISA

Recommended dilution:

 WB  1:1,000-2,000     IHC 1:100-200     ELISA  1:10,000-20,000

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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Email: info@sobekbio.com

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