Background:

p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms .

Alternative names:

N/A

Clonality:

Monoclonal

Species reactivity:

Human, Rat, Mouse

Source:

Mouse

Species:

Human

Cellular localization:

Nucleus

Isotype:

IgG1

Immunogen:

Synthetic Peptide

Concentration:

1mg/ml

Observed band:

50-80kDa

Applications:

WB, IHC

Recommended dilution:

WB 1:1,000-2,000   IHC:1;100-1:200

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com