Background:

ACSS1 (acyl-CoA synthetase short-chain family member 1), also known as ACAS2L or AceCS2L, is a 689 amino acid protein that localizes to the mitochondrial matrix and belongs to the ATP-dependent AMP-binding enzyme family. Functioning primarily as a cardiac enzyme, ACSS1 catalyzes the ATP-dependent conversion of acetate and CoA (coenzyme A) to acetyl-CoA, which is then utilized for the oxidation of acetate within the tricarboxylic acid cycle. ACSS1 is expressed as two alternatively spliced isoforms and is encoded by a gene which maps to chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.

Alternative names:

ACSS1; ACAS2L; KIAA1846; Acetyl-coenzyme A synthetase 2-like; mitochondrial; Acetate--CoA ligase 2; Acetyl-CoA synthetase 2; AceCS2; Acyl-CoA synthetase short-chain family member 1

Clonality:

Polyclonal

Reactivity:

Human,Mouse

Source:

Rabbit

Isotype:

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Immunogen:

Synthesized peptide derived from the C-terminal region of human ACSS1. at AA rangle； 580-660

Concentration:

1mg/ml

Applications:

WB, IHC, ELISA

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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