AIM2 Rabbit pAb ES1617
Specifications
| 50µl / 100µl |
Background:
Absent in melanoma 2 (AIM2) is a sensor of cytosolic DNA that is responsible for activation of the inflammasome and host immune responses to DNA viruses and intracellular bacteria . Upon binding to DNA, it is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Otherwise, it functions as a tumor suppressor which may act by repressing NF-kappa-B transcriptional activity .
Alternative names:
AIM2; Interferon-inducible protein AIM2; Absent in melanoma 2
Clonality:
Polyclonal
Reactivity:
Human
Source:
Rabbit
Isotype:
Request info at info@sobekbio.com
Immunogen:
Synthesized peptide derived from the Internal region of human AIM2. at AA rangle; 30-110
Concentration:
1mg/ml
Applications:
WB, IHC, IF, ELISA
Recommende dilutions:
Request info at info@sobekbio.com
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
