Background:

The armadillo (ARM) repeat family of proteins are related to the Drosophila melanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cell migration, cell proliferation, tissue maintenance and tumorigenesis. They are intracellular proteins that function in signal transduction and cell structure. ARMCX1 (armadillo repeat containing, X-linked 1), also known as ALEX1 (arm protein lost in epithelial cancers, X chromosome, 1), is a 453 amino acid single-pass membrane protein expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon and expressed at very low levels in liver and thymus. Containing three ARM repeats, ARMCX1 may play a role in tumor suppression. ARMCX1 is significantly down-regulated in human lung, prostate, colon, pancreas and ovarian carcinomas.

Alternative names:

ARMCX1; ALEX1; AD032; Armadillo repeat-containing X-linked protein 1; ARM protein lost in epithelial cancers on chromosome X 1; Protein ALEX1

Clonality:

Polyclonal

Reactivity:

Human

Source:

Rabbit

Isotype:

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Immunogen:

Synthesized peptide derived from the N-terminal region of human ARMCX1. at AA rangle； 10-90

Concentration:

1mg/ml

Applications:

WB, IHC, IF, ELISA

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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