Background:

ASF1A (anti-silencing function 1A) is a transcription factor that has been shown to bind with HeLa cell core Histones H3 and H4. Human ASF1A, which shares 71% amino acid identity to ASF1B, is believed to act as a chaperone to derepress genes since that action is observed in yeast Asf1A. High phosphorylation of ASF1A is demonstrated during the S-phase of the cell cycle. Both ASF1A and B are phosophorylated by the proteins TLK1 and TLK2. The ASF1B gene has been mapped to chromosome 19p13.13 while the ASF1A gene localizes to 6q22.31. ASF1A and B cooperate in the formation of nucleosomes along with the protein CAF1.

Alternative names:

ASF1A; CGI-98; HSPC146; Histone chaperone ASF1A; Anti-silencing function protein 1 homolog A; hAsf1; hAsf1a; CCG1-interacting factor A; CIA; hCIA

Clonality:

Polyclonal

Reactivity:

Human,Mouse

Source:

Rabbit

Isotype:

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Immunogen:

Synthesized peptide derived from the Internal region of human Asf1a. at AA rangle； 90-170

Concentration:

1mg/ml

Applications:

WB, IF, ELISA

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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Orders:

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