Background:

The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Cytochrome c oxidase 17 (COX17) is a nuclear gene encoding a mitochondrial copper chaperone protein necessary for proper COX apoenzyme-dependent mitochondrial respiration. COX17 is a highly conserved protein and influences the recruitment of copper ions to the mitochondria for delivery and incorporation into the COX apoenzyme.

Alternative names:

COX17; Cytochrome c oxidase copper chaperone

Clonality:

Polyclonal

Reactivity:

Human,Mouse,Rat

Source:

Rabbit

Isotype:

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Immunogen:

Synthesized peptide derived from the N-terminal region of human COX17. at AA rangle； 1-80

Concentration:

1mg/ml

Applications:

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Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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