Background:

Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing ara-chidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). Cytochrome P450 4A11 (CYP4A11), also known as CP4Y, CYP4A2, P450HL-omega or CYP4AII, is a 519 amino acid protein that is expressed in kidney and liver. Localized to the membrane of the endoplasmic reticulum, CYP4A11 uses heme as a cofactor to catalyze the oxygen-dependent hydroxylation of medium-chain fatty acids, such as myristate, laurate and palmitate, thereby playing an important role in fatty acid metabolism. CYP4A11 exists as two isoforms that are produced by alternative splicing events.

Alternative names:

CYP4A11; CYP4A2; Cytochrome P450 4A11; 20-hydroxyeicosatetraenoic acid synthase; 20-HETE synthase; CYP4AII; CYPIVA11; Cytochrome P-450HK-omega; Cytochrome P450HL-omega; Fatty acid omega-hydroxylase; Lauric acid omega-hydroxylase; CYP4A22; C

Clonality:

Polyclonal

Reactivity:

Human

Source:

Rabbit

Isotype:

Request info at info@sobekbio.com

Immunogen:

Synthesized peptide derived from the Internal region of human CYP4A11/22. at AA rangle； 360-440

Concentration:

1mg/ml

Applications:

Request info at info@sobekbio.com

Recommende dilutions:

Request info at info@sobekbio.com

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com