GRK 2 Rabbit pAb ES2477
Specifications
| 50µl / 100µl |
Background:
Beta-adrenergic receptor kinase 1 phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Beta-adrenergic receptor kinase 1 is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Alternative names:
ADRBK1; BARK; BARK1; GRK2; Beta-adrenergic receptor kinase 1; Beta-ARK-1; G-protein coupled receptor kinase 2
Clonality:
Polyclonal
Reactivity:
Human,Mouse,Rat
Source:
Rabbit
Isotype:
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Immunogen:
Synthesized peptide derived from the C-terminal region of human GRK 2. at AA rangle; 570-650
Concentration:
1mg/ml
Applications:
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Recommende dilutions:
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Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
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Orders:
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