Background:

MLKL belongs to the protein kinase superfamily. Mixed lineage kinase domain-like protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. Mixed lineage kinase domain-like protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway.

Alternative names:

MLKL; Mixed lineage kinase domain-like protein

Clonality:

Polyclonal

Reactivity:

Human

Source:

Rabbit

Isotype:

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Immunogen:

Synthesized peptide derived from the N-terminal region of human MLKL. at AA rangle； 40-120

Concentration:

1mg/ml

Applications:

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Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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