Background:

Methylenetetrahydrofolate reductase encoded by MTHFR catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Alternative names:

MTHFR; Methylenetetrahydrofolate reductase

Clonality:

Polyclonal

Reactivity:

Human,Mouse,Monkey

Source:

Rabbit

Isotype:

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Immunogen:

Synthesized peptide derived from the Internal region of human MTHFR.

Concentration:

1mg/ml

Applications:

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Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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