PUMA Rabbit pAb ES3285
Specifications
| 50µl / 100µl |
Background:
BBC3 encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. BCL2 binding component 3 cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, BBC3 is a potential drug target for cancer therapy and for tissue injury.
Alternative names:
BBC3; PUMA; Bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis
Clonality:
Polyclonal
Reactivity:
Human,Mouse,Rat
Source:
Rabbit
Isotype:
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Immunogen:
Synthesized peptide derived from the C-terminal region of human PUMA.
Concentration:
1mg/ml
Applications:
WB, ELISA
Recommende dilutions:
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Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
Email: info@sobekbio.com
Orders:
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