Topo IIIβ-1 Rabbit pAb ES3627
Specifications
| 50µl / 100µl |
Background:
TOP3B encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Alternative names:
TOP3B; TOP3B1; DNA topoisomerase 3-beta-1; DNA topoisomerase III beta-1
Clonality:
Polyclonal
Reactivity:
Human,Mouse
Source:
Rabbit
Isotype:
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Immunogen:
Synthesized peptide derived from the N-terminal region of human Topo IIIβ-1. at AA rangle； 30-110
Concentration:
1mg/ml
Applications:
WB, IHC, ELISA
Recommende dilutions:
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Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
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Orders:
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