ELK Biotechnology

ELK biotechnology is a high-tech biological company focusing on the development and production of immune products and molecular biology products.
Their products cover around 8.000+ ELISA kits, 11.000+ antibodies, and multiple kinds of genome extraction reagents, molecular biology reagents and cell experiment related products.
ELK Biotechnology is involved in immunochemistry, tumor research, neurobiology, cell cycle, signal transduction among other fields.
Their products have strict R&D and quality inspection processes, for this reason each product has complete R&D, production and quality inspection records.

While developing, ELK Biotechnology always implements the concept of environmental protection in their production processes, and always takes scientific development and environmental protection as their company's mission. In line with the belief of providing scientists with the most cutting-edge and most cost-effective research tools, ELK Biotechnology will continue to devote themselves to providing high-quality scientific research products for scientific researchers and contributing to the development of human life sciences.

The prices are on request! Contact Us by e-mail info@sobekbio.com

TRAF6 Rabbit pAb ES3636

The add to cart button will appear once you select the values above

Specifications

size	50µl / 100µl

Background:

TNF receptor-associated factor 6 encoded by TRAF6 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.

Alternative names:

TRAF6; RNF85; TNF receptor-associated factor 6; E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer; RING finger protein 85

Clonality:

Polyclonal

Reactivity:

Human,Mouse,Rat

Source:

Rabbit

Isotype:

Request info at info@sobekbio.com

Immunogen:

Synthesized peptide derived from the Internal region of human TRAF6.

Concentration:

1mg/ml

Applications:

WB, IHC, ELISA

Recommende dilutions:

Request info at info@sobekbio.com

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com