ELK Biotechnology

ELK biotechnology is a high-tech biological company focusing on the development and production of immune products and molecular biology products.
Their products cover around 8.000+ ELISA kits, 11.000+ antibodies, and multiple kinds of genome extraction reagents, molecular biology reagents and cell experiment related products.
ELK Biotechnology is involved in immunochemistry, tumor research, neurobiology, cell cycle, signal transduction among other fields.
Their products have strict R&D and quality inspection processes, for this reason each product has complete R&D, production and quality inspection records.

While developing, ELK Biotechnology always implements the concept of environmental protection in their production processes, and always takes scientific development and environmental protection as their company's mission. In line with the belief of providing scientists with the most cutting-edge and most cost-effective research tools, ELK Biotechnology will continue to devote themselves to providing high-quality scientific research products for scientific researchers and contributing to the development of human life sciences.

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RSAD2 Rabbit pAb ES4264

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Specifications

size	50µl / 100µl

Background:

RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2) is a Protein Coding gene. Diseases associated with RSAD2 include influenza and encephalitis. Among its related pathways are Immune System and Interferon gamma signaling. Gene Ontology (GO) annotations related to this gene include protein self-association and iron-sulfur cluster binding. Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV), hepatitis C virus (HCV), west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV), and human immunodeficiency virus (HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.

Alternative names:

RSAD2; CIG5; Radical S-adenosyl methionine domain-containing protein 2; Cytomegalovirus-induced gene 5 protein; Viperin; Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible

Clonality:

Polyclonal

Reactivity:

Human

Source:

Rabbit

Isotype:

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Immunogen:

Synthesized peptide derived from the N-terminal region of human RSAD2.

Concentration:

1mg/ml

Applications:

WB, IHC, ELISA

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

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