ELK Biotechnology

ELK biotechnology is a high-tech biological company focusing on the development and production of immune products and molecular biology products.
Their products cover around 8.000+ ELISA kits, 11.000+ antibodies, and multiple kinds of genome extraction reagents, molecular biology reagents and cell experiment related products.
ELK Biotechnology is involved in immunochemistry, tumor research, neurobiology, cell cycle, signal transduction among other fields.
Their products have strict R&D and quality inspection processes, for this reason each product has complete R&D, production and quality inspection records.

While developing, ELK Biotechnology always implements the concept of environmental protection in their production processes, and always takes scientific development and environmental protection as their company's mission. In line with the belief of providing scientists with the most cutting-edge and most cost-effective research tools, ELK Biotechnology will continue to devote themselves to providing high-quality scientific research products for scientific researchers and contributing to the development of human life sciences.

The prices are on request! Contact Us by e-mail info@sobekbio.com

WAVE2 Rabbit pAb ES4431

The add to cart button will appear once you select the values above

Specifications

size	50µl / 100µl

Background:

WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in actin polymerization and cytoskeletal organization. The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the actin cytoskeleton. The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating actin reorganization downstream of the Rho family of small GTPases. The two protein homologs WAVE1 and WAVE2 specifically regulate membrane ruffling by inducing the formation of actin filament clusters in response to GTP binding and activating Rac. The WAVE proteins mediate this actin polymerization by cooperating with the Arp2/3 complex, a nucleation core, and thereby promoting the formation of actin filaments. WAVE1, which is also designated SCAR (for suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed with the expression highest in peripheral blood leukocytes. WAVE3 forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function.

Alternative names:

WASF2; WAVE2; Wiskott-Aldrich syndrome protein family member 2; WASP family protein member 2; Protein WAVE-2; Verprolin homology domain-containing protein 2

Clonality:

Polyclonal

Reactivity:

Human,Mouse,Rat

Source:

Rabbit

Isotype:

Request info at info@sobekbio.com

Immunogen:

Synthesized peptide derived from the Internal region of human WAVE2. at AA rangle； 110-190

Concentration:

1mg/ml

Applications:

WB, IHC, ELISA

Recommende dilutions:

Request info at info@sobekbio.com

Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com