MDM2 Rabbit pAb ES6212
Specifications
| 50µl / 100µl |
Background:
MDM2 (MDM2 proto-oncogene) encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for MDM2 on chromosome 2.
Alternative names:
MDM2; E3 ubiquitin-protein ligase Mdm2; Double minute 2 protein; Hdm2; Oncoprotein Mdm2; p53-binding protein Mdm2
Clonality:
Polyclonal
Reactivity:
Human
Source:
Rabbit
Isotype:
Request info at info@sobekbio.com
Immunogen:
Synthesized peptide derived from human MDM2 around the non-phosphorylation site of S186/S188.
Concentration:
1mg/ml
Applications:
IHC, IF, WB, ELISA
Recommende dilutions:
Request info at info@sobekbio.com
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com
