Background:

EIF2AK4 encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the down regulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.

Alternative names:

EIF2AK4; GCN2; KIAA1338; Eukaryotic translation initiation factor 2-alpha kinase 4; GCN2-like protein

Clonality:

Polyclonal

Reactivity:

Human,Mouse

Source:

Rabbit

Isotype:

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Immunogen:

Synthesized peptide derived from human GCN2 around the non-phosphorylation site of T899.

Concentration:

1mg/ml

Applications:

IHC, ELISA

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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