Nephrin Rabbit pAb ES6411
Specifications
| 50µl / 100µl |
Background:
NPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. NPHS1 is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
Alternative names:
NPHS1; NPHN; Nephrin; Renal glomerulus-specific cell adhesion receptor
Clonality:
Polyclonal
Reactivity:
Human,Mouse,Rat
Source:
Rabbit
Isotype:
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Immunogen:
Synthesized peptide derived from the C-terminal region of human Nephrin.
Concentration:
1mg/ml
Applications:
IHC, ELISA
Recommende dilutions:
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Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
Email: info@sobekbio.com
Orders:
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