Background:

The protein encoded by SOD1 (superoxide dismutase 1, soluble) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in SOD1 have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for SOD1.

Alternative names:

SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1

Clonality:

Polyclonal

Reactivity:

Human,Mouse,Rat

Source:

Rabbit

Isotype:

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Immunogen:

Synthesized peptide derived from the Internal region of human SOD-1.

Concentration:

1mg/ml

Applications:

WB, IHC

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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