Crystallin-αC Rabbit pAb ES8266
Specifications
| 50µl / 100µl |
Background:
The protein encoded by HSPB8 (heat shock protein family B (small) member 8) belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in HSPB8 have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Alternative names:
N/A
Clonality:
Polyclonal
Reactivity:
Human
Source:
Rabbit
Isotype:
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Immunogen:
Recombinant Protein
Concentration:
1mg/ml
Applications:
WB
Recommende dilutions:
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Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
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Orders:
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