Background:

Calcium binding proteins are an important component of calcium mediated cellular signal transduction. CABP1 (calcium binding protein 1) encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by CABP1 regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. CABP1 is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms.

Alternative names:

N/A

Clonality:

Polyclonal

Reactivity:

Mouse,Rat

Source:

Rabbit

Isotype:

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Immunogen:

Synthetic Peptide

Concentration:

1mg/ml

Applications:

WB, IHC

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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