Background:

C8B (complement C8 beta chain) encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants.

Alternative names:

Complement component C8 beta chain (Complement component 8 subunit beta)

Clonality:

Polyclonal

Reactivity:

Human,Rat

Source:

Rabbit

Isotype:

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Immunogen:

Synthesized peptide derived from C8 β at AA range； 371-420

Concentration:

1mg/ml

Applications:

WB, ELISA

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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