Background:

FOXO4, also named as AFX, AFX1 and MLLT7, is a transcription factor which involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1.FOXO down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias. The antiboay can recognize isoform 1 and isoform Zeta of FOXO4.

Alternative names:

Forkhead box protein O4 (Fork head domain transcription factor AFX1)

Clonality:

Polyclonal

Reactivity:

Human

Source:

Rabbit

Isotype:

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Immunogen:

Synthetic Acetyl peptide from human protein at AA range； 189

Concentration:

1mg/ml

Applications:

WB, ELISA

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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