Background:

PF-4 encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. PF-4is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. PF4 (Platelet Factor 4) is a Protein Coding gene. Diseases associated with PF4 include Erythromelalgia and Thrombocytopenia. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Akt Signaling.

Alternative names:

Platelet factor 4 (PF-4) (C-X-C motif chemokine 4) (Iroplact) (Oncostatin-A) [Cleaved into； Platelet factor 4, short form]

Clonality:

Polyclonal

Reactivity:

Human,Rat

Source:

Rabbit

Isotype:

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Immunogen:

Synthetic peptide from human protein at AA range； 51-100

Concentration:

1mg/ml

Applications:

IHC, ELISA

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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