Background:

KAT6B (Lysine Acetyltransferase 6B) is a Protein Coding gene. Diseases associated with KAT6B include Genitopatellar Syndrome and Sbbyss Syndrome. Among its related pathways are Chromatin organization. The protein encoded by KAT6B is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of KAT6B and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for KAT6B.

Alternative names:

N/A

Clonality:

Polyclonal

Reactivity:

Human,Mouse

Source:

Rabbit

Isotype:

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Immunogen:

Synthesized peptide derived from human protein . at AA range； 1170-1250

Concentration:

1mg/ml

Applications:

WB, ELISA

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

More info:

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