SOCS7 Rabbit pAb ES10321
Specifications
| 50µl / 100µl |
Background:
SOCS7 (Suppressor Of Cytokine Signaling 7) is a Protein Coding gene. Among its related pathways are Jak-STAT signaling pathway (KEGG) and Prolactin Signaling Pathway. Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Alternative names:
N/A
Clonality:
Polyclonal
Reactivity:
Human,Mouse
Source:
Rabbit
Isotype:
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Immunogen:
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Concentration:
1mg/ml
Applications:
WB, ELISA
Recommende dilutions:
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Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
Email: info@sobekbio.com
Orders:
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