Background:

TNN (Tenascin N) is a Protein Coding gene. Diseases associated with TNN include Adhesive Otitis Media and Chronic Purulent Otitis Media. Among its related pathways are ECM proteoglycans and Focal Adhesion. Extracellular matrix protein that seems to be a ligand for ITGA8: ITGB1, ITGAV: ITGB1 and ITGA4: ITGB1. Involved in neurite outgrowth and cell migration in hippocampal explants. During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells. Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells.

Alternative names:

N/A

Clonality:

Polyclonal

Reactivity:

Human,Mouse

Source:

Rabbit

Isotype:

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Immunogen:

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Concentration:

1mg/ml

Applications:

WB, ELISA

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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