Background:

USP49 (Ubiquitin Specific Peptidase 49) is a Protein Coding gene. Among its related pathways are Deubiquitination and Metabolism of proteins. GO annotations related to this gene include histone binding and cysteine-type peptidase activity. Specifically deubiquitinates histone H2B at Lys-120 (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.

Alternative names:

N/A

Clonality:

Polyclonal

Reactivity:

Human,Mouse

Source:

Rabbit

Isotype:

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Immunogen:

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Concentration:

1mg/ml

Applications:

WB, ELISA

Recommende dilutions:

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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