TAB3 Rabbit pAb ES10566
Specifications
| 50µl / 100µl |
Background:
The product of TAB3 (TGF-Beta Activated Kinase 1 And MAP3K7 Binding Protein 3) functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Alternative names:
N/A
Clonality:
Polyclonal
Reactivity:
Human,Mouse
Source:
Rabbit
Isotype:
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Immunogen:
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Concentration:
1mg/ml
Applications:
WB, ELISA
Recommende dilutions:
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Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
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Orders:
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