ING3 Rabbit pAb ES10794
Specifications
| 50µl / 100µl |
Background:
Inhibitor Of Growth Family Member 3 encoded by ING3 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
Alternative names:
N/A
Clonality:
Polyclonal
Reactivity:
Human,Mouse,Rat
Source:
Rabbit
Isotype:
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Immunogen:
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Concentration:
1mg/ml
Applications:
WB, ELISA
Recommende dilutions:
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Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
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Orders:
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