Bub3 Rabbit pAb ES1800
Specifications
| 50µl / 100µl |
Background:
BUB3 is a conserved component of the mitotic spindle assembly complex and is an essential compent of spindle-assembly checkpoint (SAC) signaling that operates during early embryogenesis. BUB3 null embryos treated with a spindle-depolymerising agent fail to arrest in metaphase and show an increase in mitotic disarray. In mitosis, the SAC prevents anaphase onset until all chromosomes have been attached to the spindle microtubules and aligned correctly at the equatorial metaphase plate. BUB3 is involved in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments in mammalian oocyte meiosis.
Alternative names:
BUB3; Mitotic checkpoint protein BUB3
Clonality:
Polyclonal
Reactivity:
Human,Mouse,Rat
Source:
Rabbit
Isotype:
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Immunogen:
Synthesized peptide derived from the C-terminal region of human Bub3. at AA rangle; 260-340
Concentration:
1mg/ml
Applications:
WB, IHC, IF, ELISA
Recommende dilutions:
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Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
More info:
Email: info@sobekbio.com
Orders:
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