Background:

The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa.  It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.

Alternative names:

LAMP-1,Lysosome-associated membrane glycoprotein 1, lysosomal membrane glycoprotein 1, CD107 antigen-like family member A, lysosome-associated membrane protein 1

Description:

Antibody for flow cytometry

Species reactivity:

Mouse

Host:

Rat

Isotype:

Rat IgG2a,κ

Concentration:

Request info at info@sobekbio.com

Buffer:

PBS with 0.05% Proclin300, 1% BSA

Conjugation:

PE/Cyanine7

Applications:

FCM

Storage:

Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com