Background:

This product is a FCM antibody cocktail made up of FITC Anti-Human CD3 Antibody [Clone: OKT3] (Mouse IgG2a, κ),PE Anti-Human CD4 Antibody [Clone: RPA-T4] (Mouse IgG1, κ) and PerCP/Cyanine5.5 Anti-Human CD45 Antibody [Clone: HI30] (Mouse IgG1, κ). CD3 is a heterotetrameric protein consisting of a CD3γ, a CDδ and 2 CD3ε. It forms complex with TCR. OKT-3 recognize human CD3ε. Human CD3 is expressed on the surface of T cells and NKT cells. CD4 is also called Leu-3 or T4. It's a single-chain type I transmembrane glycoprotein, mainly expressed on the surface of T cells, and monocytes/macrophages. In T cells, CD4 forms complex with TCR/CD3 and play important roles in T cell immunity. The target of HIV is CD4+ T cells. Reduction of CD4+ T cells is the main reason of defected immunity after HIV infection. CD45 is a single-chain type I transmembrane glycoprotein. Except for erythrocytes and platelets, CD45 is expressed on nearly all of the hematopoietic cells with high level. It is a common marker for blood leukocytes. CD45 is a receptor type protein tyrosine phophatase and plays essential roles in B cell and T cells signaling.

Alternative names:

N/A

Description:

Antibody for flow cytometry

Species reactivity:

Human

Host:

Isotype:

Concentration:

Request info at info@sobekbio.com

Buffer:

PBS with 0.05% Proclin300, 1% BSA

Conjugation:

FITC,PE,PerCP/Cyanine5.5

Applications:

FCM

Storage:

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com