Background:

CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Alternative names:

Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119

Description:

Antibody for flow cytometry

Species reactivity:

Mouse

Host:

Rat

Isotype:

Rat IgG2a, κ

Concentration:

0.5 mg/mL

Buffer:

PBS with 0.05% Proclin300, 1% BSA

Conjugation:

Biotin

Applications:

FCM

Storage:

Store at 2~8°C. Do not freeze.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com