Background:

CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.

Alternative names:

Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5

Description:

Antibody for flow cytometry

Species reactivity:

Human

Host:

Mouse

Isotype:

Mouse IgG2a, κ

Concentration:

Request info at info@sobekbio.com

Buffer:

PBS with 0.05% Proclin300, 1% BSA

Conjugation:

PerCP/Cyanine5.5

Applications:

FCM

Storage:

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com